Description
InformationUNC0379 UNC0379 is a selective, substrate competitive inhibitor of N-lysine methyltransferase SETD8 with IC50 of 7.9 µM, high selectivity over 15 other methyltransferases.TargetsSETD8 (Cell-free assay) 7.3 µMIn vitroUNC0379 is competitive with the peptide substrate and noncompetitive with the cofactor SAM